Telomerase: Optimism for cancer marker grows
نویسندگان
چکیده
منابع مشابه
Evidence grows for high-field MRI’s value in prostate cancer
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متن کاملTelomerase and cancer.
Telomerase, a eukaryotic ribonucleoprotein (RNP) complex, contains both an essential RNA and a protein reverse transcriptase subunit. By reverse transcription, the telomerase RNP maintains telomere length stability in almost all cancer cells. Over the past few years there has been significant progress in identifying the components of the telomerase holoenzyme complex and the proteins that assoc...
متن کاملTelomerase RNA as a detection marker in the serum of breast cancer patients.
Tumor-derived circulating DNA has been found in the plasma of cancer patients. Alterations include decreased strand stability, mutations of oncogenes or of tumor suppressor genes, microsatellite alterations, and hypermethylation of several genes. RNA has also been found circulating in the plasma of normal subjects and cancer patients. Tyrosinase mRNA has been extracted from the serum of melanom...
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BACKGROUND A study was undertaken to evaluate the usefulness of telomerase activity assay in transthoracic fine needle biopsy (TFNB) aspirates collected from peripheral tumours of the lung in predicting the malignant aetiology of lung infiltrations. METHODS 100 patients with a peripheral infiltration of the lung underwent TFNB of the focal lesion. The aspirates were subjected to standard cyto...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1995
ISSN: 0923-7534
DOI: 10.1093/oxfordjournals.annonc.a059266